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Wikenigma - an Encyclopedia of Unknowns Wikenigma - an Encyclopedia of the Unknown


Lacosamide - sold under the brand name Vimpat and others - was discovered at the University of Houston in 1996. It was licenced in Europe and the US in 2008 for the treatment of partial-onset seizures in Epilepsyplugin-autotooltip__plain plugin-autotooltip_bigEpilepsy

"Epilepsy is a chronic noncommunicable disease of the brain that affects around 50 million people worldwide. It is characterized by recurrent seizures, which are brief episodes of involuntary movement that may involve a part of the body (partial) or the entire body (generalized) and are sometimes accompanied by loss of consciousness and control of bowel or bladder function. Seizure episodes are a result of excessive electrical discharges in a group of brain cells. Different parts of โ€ฆ

Its precise mechanism of action was unknown at the time of approval, and the exact amino acid targets involved remain uncertain to this day."

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The drug has also been used (with varying degrees of success) to treat : bipolar disorder, cocaine addiction, dementia, depression, diabetic peripheral neuropathy, fibromyalgia, headache, hiccups, Huntington's disease, mania, migraine, obsessive-compulsive disorder, panic disorder, restless leg syndrome, and tinnitus.

In no case has the drug's mechanism of action been fully explained.

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