Crohn's disease is a type of inflammatory bowel disease (IBD) that can affect any part of the entire digestive tract. It causes inflammation and in severe cases, ulcers can form. Symptoms often include abdominal pain, diarrhea, fever, abdominal distension, and weight loss.
The cause of Crohn's disease is unknown. Researchers think that an autoimmune reaction may be one cause. An autoimmune reaction happens when your immune system attacks healthy cells in your body. Genetics may also play a role, since Crohn's disease can run in families.
Stress and eating certain foods don't cause the disease, but they can make your symptoms worse.
Source : MedlinePlus. US National Library of Medicine.
As well as genetics, faulty immune system balance, microbial infections, and environmental factors are also under investigation as possible contributing factors. See: Wikipedia
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