Random article ( of 1089 ) Latest updates

User Tools

Site Tools


content:life_sciences:life_itself:cell_size

Wikenigma - an Encyclopedia of Unknowns Wikenigma - an Encyclopedia of the Unknown

Cell size

A detailed explanation of the factors which regulate cell size (i.e. the size to which cells grow) has not yet been found. Since (most) cells stop growing when they reach a specific size, it's suggested that there must be some feedback mechanism to restrict growth beyond that point.

The existence of a “size control” is well known and the control has been studied for a long time, but it has been remarkably resistant to molecular analysis. The attainment of a critical size triggers the periodic events of the cycle such as the S period and mitosis. This control acts as a homeostatic effector that maintains a constant “average” cell size at division through successive cycles in a growing culture. It is a vital link coordinating cell growth with periodic events of the cycle. A size control is present in all the systems and appears to operate near the start of S or of mitosis when the cell has reached a critical size, but the molecular mechanism by which size is measured remains both obscure and a challenge."

Source : Growth dung the cell cycle (paywalled)International Review of Cytology, Volume 226, 2003, Pages 165-258

Also see : Cell proliferationplugin-autotooltip__plain plugin-autotooltip_bigCell proliferation

When organic 'tissue' grows (either during embryonic development, post-natal growth, or tissue regeneration) there are two processes in operation which determine the final size of the tissue or organ. The first is the size of the cells themselves - which is governed by an as yet unknown process (see:

Importance Rating

THIS WEBSITE DOES NOT USE TRACKING, ADVERTISING, OR ANALYTICAL COOKIES OF ANY KIND. All essential cookies (for login status etc) are automatically deleted at the end of the session . . . full details here

Show another (random) article

Suggestions for corrections and ideas for articles are welcomed : Get in touch!


Further resources :