βThe mechanisms that link cellular differentiation programs and dynamic gene regulation in complex eukaryotic systems remain mysterious. Such programs drive diverse and central biological processes including organismal development, immune function, disease progression, and meiosis.β
Source : The Brar Lab at Berkeley
Although there has been extensive progress in the understanding of factors involved with cellular differentiation, a full description of how stem cells differentiate into radically different forms (to generate the diverse structure of complex organisms) is elusive.
Each cell of a mammal (for example) carries the full genetic code to form any cell within the body. As an embryo develops, multiple sets of genes are 'turned off' within a cell, leaving the only the correct set operating to form the target cell.
There are many theoretical proposals to explain how this occurs - including 'epigenetic' factors (i.e. outside the chromosomes) e.g. hormones etc. - which might influence the growth and final destiny of a cell.
Also see :
Ideas for new topics, and suggested additions / corrections for older ones, are always welcome.
If you have skills or interests in a particular field, and have suggestions for Wikenigma, get in touch !
Or, if you'd like to become a regular contributor . . . request a login password. Registered users can edit the entire content of the site, and also create new pages.
( The 'Notes for contributors' section in the main menu has further information and guidelines etc.)
You are currently viewing an auto-translated version of Wikenigma
Please be aware that no automatic translation engines are 100% accurate, and so the auto-translated content will very probably feature errors and omissions.
Nevertheless, Wikenigma hopes that the translated content will help to attract a wider global audience.