[The] Clemmensen reduction is a chemical reaction described as a reduction of ketones (or aldehydes) to alkanes using zinc amalgam and concentrated hydrochloric acid .
Source : Wikipedia
The reaction, which is used for converting a carbonyl group into a methylene group, was developed in the early 20th century.by the Danish chemist Erik Christian Clemmensen.
The replacement of the oxygen atoms of the carbonyl group in an aldehyde or ketone by two hydrogen atoms through the use of amalgamated zinc and hydrochloric acid was first employed in 1913 by Clemmensen and is know as the Clemmensen method of reduction. The process has been applied to a large number of aldehydes and ketones as a step in the synthesis of polynuclear hydrocarbons and alkylated aromatic compounds. It has also played an important role in the elucidation of the structures of highly complex natural products.
Source : Organic Reactions [reference book]
Despite a century or so of widespread use in the laboratory and in industry, an exact description of the chemical mechanisms of the reaction is still lacking.
Ideas for new topics, and suggested additions / corrections for old ones, are always welcome.
If you have skills or interests in a particular field, and have suggestions for Wikenigma, get in touch !
Or, if you'd like to become a regular contributor . . . request a login password. Registered users can edit the entire content of the site, and also create new pages.
( The 'Notes for contributors' section in the main menu has further information and guidelines etc.)
You are currently viewing an auto-translated version of Wikenigma
Please be aware that no automatic translation engines are 100% accurate, and so the auto-translated content will very probably feature errors and omissions.
Nevertheless, Wikenigma hopes that the translated content will help to attract a wider global audience.