====== Meprobamate ====== //Meprobamate//, sold under the brand names //Miltown, Equalnil, Meproban, Procalmidol, Sedanyl,// and more than 100 others ([[https://webbook.nist.gov/cgi/cbook.cgi?ID=57-53-4|ref.]]) is a widely-used drug used to treat anxiety (i.e. an //anxiolytic//). Its chemical formula is C9H18N2O4 , It was first synthesized in the 1950s, and has been described as //"the first blockbuster psychotropic drug in American history"// ( [[https://en.wikipedia.org/wiki/Meprobamate#History|ref.]]) earning 100s of millions of dollars for its (various) manufacturers. It's known that meprobamate has barbiturate-like modulating actions on GABAA receptors, leading to sedation and altered perception of pain - but the exact mechanism of action (which is believed to operate at multiple receptor sites in the nervous system ) is lacking a complete description.