====== Cromoglicic acid ======

>//Cromoglicic acid// (INN) — also referred to as //cromolyn// (USAN), //cromoglycate //(former BAN), or //cromoglicate// — is traditionally described as a mast cell stabilizer, and is commonly marketed as the sodium salt sodium cromoglicate or cromolyn sodium. This drug prevents the release of inflammatory chemicals such as histamine from mast cells.\\ \\ Source : [[https://en.wikipedia.org/wiki/Cromoglicic_acid|Wikipedia]]

//Cromoglicic acid//  was originally derived from longstanding herbal remedies in the mid 1960s, and is now in widespread use as an active ingredient for asthma inhalers (// //sold under the brand name// Intal// and others).

As the quote explains, it's known to be a //mast cell stabilizer// (mast cells are responsible for the release of histamine and related mediators which lead to immune responses).

However, the exact mechanism by which //Cromoglicic acid  //helps to reduce the severity of [[content:medicine:diseases:a-f:asthma|asthma]] attacks is unknown. Several other compounds which are also known to be powerful mast cell stabilizers appear to have no effect on asthma.

>__The underlying mechanism of action is not fully understood; for while cromoglicate stabilizes mast cells, this mechanism is probably not why it works in asthma__\\ \\ See [[https://en.wikipedia.org/wiki/Cromoglicic_acid#Mechanism_of_action|Wikipedia]]\\