====== Cell Wall Deficient Bacteria and Disease ======

As the name suggests, Cell Wall Deficient Bacteria (CWDB) are a group of bacteria - originally identified in 1935 - which lack a normal cell wall, e.g. //Bacillus subtilis//.

Some research groups have suggested that CWDB might cause diseases in humans and other animals,<sup> </sup>but so far the experimental evidence is lacking.

A review study from 2005 found that :

>__The true relevance of cell wall-deficient bacteria (CWDB) to disease is  unknown__
>\\ Source : [[https://web.archive.org/web/20090824140149/http://www.jimronline.net/content/full/2005/58/0545.pdf|The Journal of International Medical Research 33: 1 – 20]]

//Note: //It's recently been found that 'normal' bacteria such as// E.Coli //can be converted into CWDB by a simple enzyme reaction which removes the cell wall.